How should we know what to go after in life?

That's a difficult question for most people. If you are of the praying sort, I would suggest you pray for clarity about these decisions. I personally like to ask myself, how would I be happiest spending my time? Is there something I can do that will better mankind? To me, day to day happiness and inner peace is worth much more than money. After all, in the end, we can't take it with us! Imagine that you were living the last few days of your life and looking back at it. Will you be so thankful that you have so much money in the bank? Or will you be thankful for the happy times that you had?
I wish you the best of luck with your decisions.