One can reach Muktinath Temple in several ways like by road, by flight, by helicopter, by trek. If you want to travel by road then you need to start your journey from Pokhara then Beni, Tatopani, Ghasa, Lete, Marpha, Jomsom, Kagbeni and Muktinath. The road journey is tough as road goes in high mountains and road condition also bad.
If you want to travel by flight then you need to catch flight from Pokhara to Jomsom then travel by road till Muktinath Temple which is 25 kilometers from Jomsom. If you want to travel by helicopter then you can hire it at Pokhara or Kathmandu and fly to Muktinath, best part is helicopter lands just 20 meters from the temple entrance. You can also reach Muktinath by walk 1000s trekkers finish their Annapurna Circuit trek at Muktinath, which is just below Throng La Pass.