I have a bad case of derealization. I’ve had it on and off for most of my life. I recently came across naloxone and I read in a pilot study that it was successful. Before I try it I just have some questions from some people who have taken it. 1. Does it cause side effects? 2. The research shows that it blocks “pain blocking opioids (endorphins). Endorphins are key in reducing physical pain, does this mean that if I take naloxone I will feel pain more intensely than I do now? 3. Did it help? 4. Is it a cure, or is it a temporary treatment that you use whenever you feel derealization/depersonalization coming on? Please help, i have done literally everything I know of to treat this (i.e. therapy, anti depressants, AA, exercise, diet change, suppliments, meditation) I’m out of options. Any detailed information from someone experienced in using naloxone (narcan) for depersonalization will help. thanks